Dilutions
If you need automated serial dilutions – in a single buffer or more complex dilution series in multiple buffers, HTZ’s application suite has it covered
Introduction
You would be forgiven for thinking that performing sample dilutions is simple and its what most automated liquid samplers should be good at. The reality is that even many expensive systems just don’t have the applications to cater for some of the more demanding laboratory tests and procedures.
We have been developing applications for performing complex and extensive dilution series for many years. The experience gained whilst developing fully automated instruments for tumour marker immunoassays such as HCG and, more recently, our automated IFA instruments, means we are well placed to tackle these applications. Whether it be automated serial dilutions or complex and sample specific dilutions in different solutions we have applications software to suit. For example, if it is necessary to prepare some initial diluitons in one buffer and then change to a different matrix for others this is all programmable in our CCX3 applications software.
Special Features for Serial Dilutions
A number of new features have been added to the Beeline sx instrument’s hardware and software to meet some of the unique requirements of these tests including the following:
Unlimited number of dilutions for a given sample
Control of pipetting volumes used in intermediate dilutions
Different diluents selectable for individual dilutions
Timed incubation with specific diluents as a pre-treatment
Dilution ratios infinitely controllable
Dual Nozzle probe for performing simultaneous aspiration and dispensing steps
Intelligent dilution algorithm to minimise intermediate dilutions
Mixing, washing, plus a whole range of step specific parameters
Examples of some of the tests automated which benefit from these options include:
| Rickettsia IFA IgM | Rickettsia IFA IgG |
| Bartonella IFA IgM | Bartonella IFA IgG |
| Q Fever IFA IgG | Q Fever IFA IgM |
| HCG |
To learn more about how the dilution capabilities of HTZ Workstations can benefit your particular applications then please contact us.
